Go Back   Transformations > Physical Health > Diabetes

Thread Tools
Old January 19th, 2010, 11:42 PM   #1
Sysop's Avatar
Join Date: Apr 2008
Posts: 83
Default Effect of Renin-Angiotensin System Blockade On Insulin Resistance And Inflammatory Pa

Objective:The study investigated the effect of angiotensin-receptor blockers (ARB) on glucose homeostasis and inflammatory parameters in patients with impaired glucose tolerance (IGT).
Research Design and Methods:We prospectively studied the insulin sensitivity index (ISI) and homeostasis model of insulin resistance (HOMA-IR) in 13 obese males with IGT and in 13 matched controls with normal glucose tolerance (NGT) during hyperglycemic testing over 90 minutes. Adiponectin, retinol-binding protein 4 (RBP4), and high-sensitive C-reactive protein (hs-CRP) were analyzed. Measurements were performed at baseline and after a four-week treatment with valsartan 160 mg/day. The results of the IGT and NGT groups were compared.
At baseline, HOMA-IR (IGT 4.1±3 vs. NGT 2.3± 1.0, p
Sysop is offline   Reply With Quote


Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

All times are GMT -4. The time now is 06:40 PM.

Powered by vBulletin® Version 3.7.0
Copyright ©2000 - 2022, Jelsoft Enterprises Ltd.
Copyright Transformations 1996-2009